大腸菌・サルモネラ菌遺伝子や酵母遺伝子にみられるコドン選択の偏り(図4)
大腸菌 | サルモネラ菌 | 酵母 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
アミノ酸 | コドン | tuf A-B |
omp C |
trp A-E |
thr A,B |
13453 遺伝子 |
844 遺伝子 |
G3PDH | enolase | TRP5 | CYC 1,7 |
11796 遺伝子 |
Leu | TTA | 0 | 1 | 24 | 14 | 13.6 | 13.8 | 0 | 5 | 15 | 3 | 26.3 |
TTG | 0 | 0 | 27 | 23 | 13.2 | 12.1 | 41* | 73* | 24* | 8* | 27.2* | |
CTT | 2 | 1 | 17 | 10 | 11.2 | 11.6 | 0 | 0 | 4 | 1 | 12.2 | |
CTC | 1 | 1 | 22 | 18 | 10.9 | 10.4 | 0 | 0 | 4 | 0 | 5.4 | |
CTA | 0 | 0 | 10 | 3 | 3.9 | 4.6 | 1 | 0 | 11 | 1 | 13.4 | |
CTG | 53* | 24* | 107* | 55* | 51.5* | 50.9* | 0 | 0 | 4 | 0 | 10.4 | |
Arg | CGT | 41* | 12* | 35* | 24* | 20.9* | 18.8* | 0 | 2 | 3 | 0 | 6.5 |
CGC | 5* | 1* | 57* | 23* | 21.4* | 21.9* | 0 | 0 | 1 | 0 | 2.6 | |
CGA | 0 | 0 | 4 | 6 | 3.6 | 3.7 | 0 | 0 | 0 | 0 | 3.0 | |
CGG | 0 | 0 | 3 | 12 | 5.6 | 6.6 | 0 | 0 | 0 | 0 | 1.7 | |
AGA | 0 | 0 | 2 | 0 | 2.6 | 2.8 | 22* | 26* | 22* | 5* | 21.3* | |
AGG | 0 | 0 | 1 | 2 | 1.6 | 2.0 | 0 | 0 | 2 | 1 | 9.3 | |
Pro | CCT | 0 | 0 | 12 | 6 | 7.1 | 7.5 | 1 | 1 | 11 | 4 | 13.6 |
CCC | 0 | 0 | 14 | 6 | 5.3 | 6.0 | 0 | 0 | 4 | 0 | 6.8 | |
CCA | 2 | 3 | 17 | 5 | 8.5 | 6.1 | 22 | 27 | 15 | 5 | 18.2 | |
CCG | 38* | 1* | 48* | 26* | 22.6* | 23.3* | 0 | 0 | 11 | 0 | 5.3 | |
Gln | CAA | 0 | 1 | 29 | 14 | 14.6 | 12.6 | 11 | 18 | 21 | 2 | 27.5 |
CAG | 16* | 20* | 58* | 32* | 29.0* | 31.4* | 0 | 0 | 6 | 3 | 12.2 | |
Lys | AAA | 35* | 17* | 55* | 24* | 34.4* | 34.4* | 3 | 10 | 18 | 14 | 42.1 |
AAG | 11 | 0 | 12 | 21 | 11.3 | 12.5 | 49* | 62* | 26* | 19* | 30.8* | |
Ala | GCT | 24* | 18* | 34* | 18* | 16.1* | 14.3* | 49* | 96* | 37* | 6* | 21.1* |
GCC | 2 | 0 | 74 | 44 | 25.1 | 27.6 | 16* | 17* | 14* | 6* | 12.6* | |
GCA | 11* | 8* | 36* | 20* | 20.5* | 13.7* | 0 | 0 | 12 | 2 | 16.2 | |
GCG | 17* | 3* | 68* | 43* | 32.6* | 39.1* | 0 | 0 | 1 | 1 | 6.1 | |
Val | GTT | 46* | 12* | 30* | 27* | 19.0* | 16.2* | 45* | 32* | 24* | 2* | 22.0* |
GTC | 1 | 2 | 22 | 22 | 14.9 | 17.4 | 27* | 37* | 24* | 1* | 11.6* | |
GTA | 21* | 9* | 16* | 8* | 11.2* | 11.9* | 0 | 0 | 6 | 1 | 11.8 | |
GTG | 6* | 2* | 50* | 32* | 25.7* | 24.6* | 0 | 0 | 7 | 2 | 10.7 | |
Gly | GGT | 38* | 29* | 53* | 31* | 25.3* | 18.4* | 49* | 72* | 52* | 16* | 23.9* |
GGC | 41* | 19* | 58* | 36* | 28.9* | 34.6* | 0* | 0* | 7* | 3* | 9.7* | |
GGA | 0 | 0 | 73 | 12 | 8.4 | 8.4 | 0 | 0 | 3 | 2 | 10.9 | |
GGG | 2 | 0 | 16 | 14 | 11.1 | 11.6 | 0 | 0 | 4 | 3 | 6.0 | |
Ser | TCT | 14 | 6 | 15 | 11 | 9.2 | 8.4 | 24* | 28* | 21* | 4* | 23.6* |
TCC | 6 | 8 | 18 | 17 | 8.9 | 10.7 | 26* | 33* | 8* | 1* | 14.2* | |
TCA | 0 | 0 | 10 | 7 | 7.7 | 7.1 | 0 | 0 | 6 | 2 | 18.7 | |
TCG | 0 | 0 | 19 | 11 | 8.7 | 9.4 | 0 | 0 | 1 | 1 | 8.6 | |
AGT | 0 | 1 | 12 | 7 | 9.0 | 7.7 | 0 | 0 | 6 | 2 | 14.2 | |
AGC | 1 | 2 | 26 | 16 | 15.6 | 17.5 | 0 | 0 | 1 | 0 | 9.7 | |
Thr | ACT | 25* | 12* | 11* | 5* | 9.5* | 7.8* | 22* | 17* | 25* | 4* | 20.2* |
ACC | 31* | 12* | 41* | 21* | 22.9* | 24.2* | 25* | 23* | 10* | 4* | 12.6* | |
ACA | 3 | 0 | 9 | 5 | 7.7 | 6.8 | 0 | 0 | 9 | 5 | 17.7 | |
ACG | 1 | 0 | 21 | 8 | 14.0 | 18.0 | 0 | 0 | 2 | 4 | 8.0 | |
Ile | ATT | 6 | 0 | 58 | 34 | 29.7 | 28.9 | 16* | 24* | 19* | 5* | 30.2* |
ATC | 52* | 10* | 39* | 26* | 24.9* | 24.1* | 23* | 19* | 12* | 3* | 17.1* | |
ATA | 0 | 0 | 2 | 2 | 5.1 | 6.1 | 0 | 0 | 3 | 1 | 17.8 | |
Asn | AAT | 0 | 0 | 29 | 28 | 18.3 | 18.6 | 0 | 2 | 11 | 3 | 36.0 |
AAC | 14* | 32* | 40* | 24* | 21.8* | 21.5* | 26* | 38* | 15* | 11* | 24.9* | |
Phe | TTT | 2 | 2 | 34 | 16 | 21.8 | 21.7 | 0 | 3 | 17 | 5 | 26.0 |
TTC | 26* | 17* | 32* | 23* | 16.6* | 15.4* | 21* | 28* | 15* | 3* | 18.2* | |
Tyr | TAT | 3 | 5 | 33 | 17 | 16.4 | 16.4 | 0 | 1 | 9 | 5 | 18.7 |
TAC | 17* | 24* | 21* | 11* | 12.3* | 11.9* | 20* | 18* | 10* | 5* | 14.7* | |
Glu | GAA | 60* | 11* | 82* | 52* | 39.8* | 36.7* | 29* | 53* | 33* | 8* | 45.9* |
GAG | 13 | 0 | 32 | 20 | 18.5 | 21.5 | 0 | 0 | 9 | 5 | 19.1 | |
Cys | TGT | 2 | 0 | 12 | 7 | 5.1 | 4.5 | 4 | 2 | 6 | 4 | 8.0 |
TGC | 4 | 0 | 18 | 16 | 6.4 | 6.3 | 0 | 0 | 1 | 1 | 4.7 | |
His | CAT | 3 | 0 | 27 | 11 | 12.6 | 11.9 | 0 | 0 | 11 | 5 | 13.7 |
CAC | 19 | 1 | 23 | 9 | 9.7 | 9.4 | 16 | 20 | 8 | 2 | 7.8 | |
Asp | GAT | 8 | 9 | 64 | 36 | 32.2 | 32.3 | 15 | 14 | 26 | 5 | 37.8 |
GAC | 41 | 23 | 37 | 18 | 19.5 | 21.2 | 30 | 47 | 14 | 4 | 20.4 | |
Met | ATG | 18 | 4 | 44 | 31 | 27.3 | 26.6 | 13 | 14 | 10 | 5 | 20.9 |
Trp | TGG | 2 | 4 | 5 | 7 | 14.4 | 12.9 | 6 | 10 | 5 | 2 | 10.3 |
大腸菌と酵母でコドン選択パターンの異なるアミノ酸種を上位に、似ているものを下位に示してある。コドンはDNA型で示した。
原図、資料:池村淑道